Anti-LRRC75B Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
FAM211B (family with sequence similarity 211, member B) is a leucine-rich repeat (LRR) protein present in viruses as well as eukaryotes. It is involved in diverse functions and is involved in protein-protein interactions. The LRR domains fold into a horseshoe (or arc) shape with a parallel β-sheet on the concave face.
Synonyms
70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70 (S6K) alpha antibody, p70 (S6K) -alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Gene Name
LRRC75B
Gene ID
388886
UniProt
Q2VPJ9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross reactivity with other proteins.
Immunogen
E.coli-derived human LRRC75B recombinant protein (Position: Q59-E283) .
Clonality
Polyclonal
Tissue Specificity
Expressed in all tissues.
Applications
Flow Cytometry
Field of Research
Signal Transduction, Signaling Pathway, Small G Proteins
Purification
Immunogen affinity purified.
Form
Liquid
Function
Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway.
References & Citations
1. Yuan, X., Waterworth, D., Perry, J. R., Lim, N., Song, K., Chambers, J. C., ... & Mooser, V. (2008) . Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. The American Journal of Human Genetics, 83 (4), 520-528. 2. Kim, Y. J., Go, M. J., Hu, C., Hong, C. B., Kim, Y. K., Lee, J. Y., ... & Cho, Y. S. (2011) . Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits. Nature genetics, 43 (10), 990-995. 3. Yang, J., Guo, F., San Chin, H., Chen, G. B., Ang, C. H., Lin, Q., ... & Fu, N. Y. (2023) . Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins. Cell Reports, 42 (2) .
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A18683-1-Fluoro488
Calculated Molecular Weight
52588 MW
Applications Notes
6
Gene Name Synonym
Serine/threonine-protein kinase AtPK1/AtPK6
Subcellular Location
Cytoplasm. Nucleus.
Protein Name
Serine/threonine-protein kinase AtPK1/AtPK6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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