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Anti-MAP1S Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Microtubule-associated protein 1S is a protein that in humans is encoded by the MAP1S gene. Enables DNA binding activity and cytoskeletal protein binding activity. Involved in microtubule bundle formation; neuron projection morphogenesis; and regulation of chromatin disassembly. Located in several cellular components, including microtubule cytoskeleton; nuclear lumen; and perinuclear region of cytoplasm.

Synonyms

Interleukin-3 receptor subunit alpha; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA; CD123; IL3RA; IL3R

Gene Name

MAP1S

Gene ID

55201

UniProt

Q66K74

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human MAP1S recombinant protein (Position: D45-H1021) .

Clonality

Polyclonal

Tissue Specificity

Brain.

Applications

Flow Cytometry

Field of Research

Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunoglobulins, Immunology, Lymphoid, Receptors, Stem Cells

Purification

Immunogen affinity purified.

Form

Liquid

Function

This is a receptor for interleukin-3.

References & Citations

1. Gross, M. B. Personal Communication. Baltimore, Md. 4/10/2014. 2. Liu, L., McKeehan, W. L. Sequence analysis of LRPPRC and its SEC1 domain interaction partners suggest roles in cytoskeletal organization, vesicular trafficking, nucleocytosolic shuttling, and chromosome activity. Genomics 79: 124-136, 2002. 3. Wang, W., Lundin, V. F., Millan, I., Zeng, A., Chen, X., Yang, J., Allen, E., Chen, N., Bach, G., Hsu, A., Maloney, M. T., Kapur, M., Yang, Y. Nemitin, a novel Map8/Map1s interacting protein with Wd40 repeats. PLoS ONE 7: e33094, 2012. Note: Electronic Article.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

Interleukin 3 receptor subunit alpha

Subcellular Location

Membrane. Single-pass type I membrane protein.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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