Anti-CBP20/NCBP2 Antibody Picoband® Fluoro594 Conjugated

Product Specifications

Background

The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

BMP and activin membrane-bound inhibitor homolog; Non-metastatic gene A protein; Putative transmembrane protein; NMA; BAMBI; NMA

Gene Name

NCBP2

Gene ID

22916

UniProt

P52298

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human CBP20/NCBP2 recombinant protein (Position: S2-N102) .

Clonality

Polyclonal

Tissue Specificity

Expressed in adult liver.

Applications

Flow Cytometry

Field of Research

Atherosclerosis, Cardiovascular, Chaperones, Heat Shock Proteins, Protein Trafficking, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Negatively regulates TGF-beta signaling.

References & Citations

1. Gebhardt, A., Habjan, M., Benda, C., Meiler, A., Haas, D. A., Hein, M. Y., Mann, A., Mann, M., Habermann, B., Pichlmair, A. mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3. Nature Commun. 6: 8192, 2015. Note: Electronic Article. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 10/28/2015. 3. Izaurralde, E., Lewis, J., Gamberi, C., Jarmolowski, A., McGuigan, C., Mattaj, I. W. A cap-binding protein complex mediating U snRNA export. Nature 376: 709-712, 1995.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

17136 MW

Applications Notes

Gene Name Synonym

BMP and activin membrane bound inhibitor

Subcellular Location

Cytoplasm . Nucleus . Translocates to nuclear foci during heat shock.

Protein Name

Chromaffin granule amine transporter

Isotype

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

More Discoveries

Explore Other Products

Browse additional items from our catalog

1203-0-010 100 µg

Anti-human high affinity IgE receptor, a-chain (FcεRIα), antibody (SR-1), 0.1% Na-azide

View Details

YP-W38131-01 48 Tests

Rat Filamin-A (FLNA) ELISA Kit

View Details

YP-W38131-02 96 Tests

Rat Filamin-A (FLNA) ELISA Kit

View Details

NB300-251PEP 0.05 mg

Notch-1 Blocking Peptide

View Details

HK206753 1 Kit

EAAT1 (SLC1A3) Human qPCR Template Standard (NM_004172)

View Details

MBS603514-01 0.1 mg

RanGAP 1

View Details

Anti-CBP20/NCBP2 Antibody Picoband® Fluoro594 Conjugated

Product Specifications

Background

Synonyms

Gene Name

Gene ID

UniProt

Host

Reactivity

Cross Reactivity

Immunogen

Clonality

Tissue Specificity

Applications

Field of Research

Purification

Form

Function

References & Citations

Storage Conditions

Calculated Molecular Weight

Applications Notes

Gene Name Synonym

Subcellular Location

Protein Name

Isotype

Contents

Explore Other Products

Anti-human high affinity IgE receptor, a-chain (FcεRIα), antibody (SR-1), 0.1% Na-azide

Rat Filamin-A (FLNA) ELISA Kit

Rat Filamin-A (FLNA) ELISA Kit

Notch-1 Blocking Peptide

EAAT1 (SLC1A3) Human qPCR Template Standard (NM_004172)

RanGAP 1