Anti-MINDY3 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
The protein encoded by this gene contains a caspase-associated recruitment domain and may function in apoptosis. It has been identified as a tumor suppressor in lung and gastric cancers, and a polymorphism in the gene may be associated with gastric cancer risk. Alternative splicing of this gene results in multiple transcript variants.
Synonyms
Protein Bop; BH3-only protein; Retrotransposon Gag-like protein 10; RTL10; BOP, C22orf29
Gene Name
MINDY3
Gene ID
80013
UniProt
Q9H8M7
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human MINDY3 recombinant protein (Position: A52-K396) .
Clonality
Polyclonal
Tissue Specificity
Ubiquitously expressed.
Applications
Flow Cytometry
Field of Research
Chemokines, Immunology, Innate Immunity
Purification
Immunogen affinity purified.
Form
Liquid
Function
Could induce apoptosis in a BH3 domain-dependent manner. The interaction network of Bcl-2 family members may play a key role in modulation RTL10/BOP intrinsic apoptotic signaling activity.
References & Citations
1. Liu, B., Liu, Y., Chen, J., Wei, Z., Yu, H., Zhen, Y., Lu, L., Hui, R. CARP is a novel caspase recruitment domain containing pro-apoptotic protein. Biochem. Biophys. Res. Commun. 293: 1396-1404, 2002. 2. Shi, Y., Chen, J., Li, Z., Zhang, Z., Yu, H., Sun, K., Wang, X., Song, X., Wang, Y., Zhen, Y., Yang, T., Lou, K., Zhang, Y., Zhang, G., Hu, Y., Ji, J., Hui, R. C10ORF97 is a novel tumor-suppressor gene of non-small-cell lung cancer and a functional variant of this gene increases the risk of non-small-cell lung cancer. Oncogene 30: 4107-4117, 2011.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
14377 MW
Applications Notes
6
Gene Name Synonym
Retrotransposon Gag like 10
Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Protein Name
Lymphocyte antigen 6A-2/6E-1
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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