Anti-NUCKS1 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
Nuclear ubiquitous casein and cyclin-dependent kinases substrate is a protein that in humans is encoded by the NUCKS1 gene. This gene encodes a nuclear protein that is highly conserved in vertebrates. The conserved regions of the protein contain several consensus phosphorylation sites for casein kinase II and cyclin-dependent kinases, two putative nuclear localization signals, and a basic DNA-binding domain. It is phosphorylated in vivo by Cdk1 during mitosis of the cell cycle.
Synonyms
Fms-related tyrosine kinase 3 ligand ; Flt3lg
Gene Name
NUCKS1
Gene ID
64710
UniProt
Q9H1E3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human NUCKS1, identical to the related mouse and rat sequences.
Clonality
Polyclonal
Applications
Flow Cytometry
Field of Research
Angiogenesis, Cardiovascular, Cytokines, Immunology, Innate Immunity
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Grundt, K., Haga, I. V., Aleporou-Marinou, V., Drosos, Y., Wanvik, B., Ostvold, A. C. Characterisation of the NUCKS gene on human chromosome 1q32.1 and the presence of a homologous gene in different species. Biochem. Biophys. Res. Commun. 323: 796-801, 2004. 2. Ostvold, A. C., Norum, J. H., Mathiesen, S., Wanvik, B., Sefland, I., Grundt, K. Molecular cloning of a mammalian nuclear phosphoprotein NUCKS, which serves as a substrate for Cdk1 in vivo. Europ. J. Biochem. 268: 2430-2440, 2001.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
25847 MW
Applications Notes
6
Gene Name Synonym
Fms-related tyrosine kinase 3 ligand
Protein Name
Uncharacterized protein
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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