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Anti-F4/80/Adgre1 Antibody Fluoro488 Conjugated

Product Specifications

Background

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and adaptive immune response. Located in external side of plasma membrane. Is expressed in several structures, including cardiovascular system; central nervous system; genitourinary system; hemolymphoid system; and intestine. Orthologous to human ADGRE1 (adhesion G protein-coupled receptor E1) .

Synonyms

Transcription factor Sp6; Krueppel-like factor 14; SP6; KLF14

Gene Name

Adgre1

Gene ID

13733

UniProt

Q61549

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived mouse F4/80/Adgre1 recombinant protein (Position: G27-S230) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

Flow Cytometry

Field of Research

Cancer, Cell Biology, Cell Cycle, Cell Division, Cell Type Marker, Cell Type Markers, Neurogenesis, Neurology Process, Neuron Marker, Neuroscience, Tags & Cell Markers, Tumor Biomarkers

Purification

Immunogen affinity purified.

Concentration

500 μg/ml

Form

Liquid

Function

Promotes cell proliferation.

References & Citations

1. Baud, V., Chissoe, S. L., Viegas-Pequignot, E., Diriong, S., N'Guyen, V. C., Roe, B. A., Lipinski, M. EMR1, an unusual member in the family of hormone receptors with seven transmembrane segments. Genomics 26: 334-344, 1995. 2. McKnight, A. J., Macfarlane, A. J., Seldin, M. F., Gordon, S. Chromosome mapping of the Emr1 gene. Mammalian Genome 8: 946-947, 1997. 3. Schulz, C., Gomez Perdiguero, E., Chorro, L., Szabo-Rogers, H., Cagnard, N., Kierdorf, K., Prinz, M., Wu, B., Jacobsen, S. E. W., Pollard, J. W., Frampton, J., Liu, K. J., Geissmann, F. A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science 336: 86-90, 2012.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

Sp6 transcription factor

Subcellular Location

Nucleus.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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