Anti-F4/80/Adgre1 Antibody Fluoro488 Conjugated
Product Specifications
Background
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and adaptive immune response. Located in external side of plasma membrane. Is expressed in several structures, including cardiovascular system; central nervous system; genitourinary system; hemolymphoid system; and intestine. Orthologous to human ADGRE1 (adhesion G protein-coupled receptor E1) .
Synonyms
Transcription factor Sp6; Krueppel-like factor 14; SP6; KLF14
Gene Name
Adgre1
Gene ID
13733
UniProt
Q61549
Host
Rabbit
Reactivity
Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived mouse F4/80/Adgre1 recombinant protein (Position: G27-S230) .
Clonality
Polyclonal
Tissue Specificity
Ubiquitous.
Applications
Flow Cytometry
Field of Research
Cancer, Cell Biology, Cell Cycle, Cell Division, Cell Type Marker, Cell Type Markers, Neurogenesis, Neurology Process, Neuron Marker, Neuroscience, Tags & Cell Markers, Tumor Biomarkers
Purification
Immunogen affinity purified.
Concentration
500 μg/ml
Form
Liquid
Function
Promotes cell proliferation.
References & Citations
1. Baud, V., Chissoe, S. L., Viegas-Pequignot, E., Diriong, S., N'Guyen, V. C., Roe, B. A., Lipinski, M. EMR1, an unusual member in the family of hormone receptors with seven transmembrane segments. Genomics 26: 334-344, 1995. 2. McKnight, A. J., Macfarlane, A. J., Seldin, M. F., Gordon, S. Chromosome mapping of the Emr1 gene. Mammalian Genome 8: 946-947, 1997. 3. Schulz, C., Gomez Perdiguero, E., Chorro, L., Szabo-Rogers, H., Cagnard, N., Kierdorf, K., Prinz, M., Wu, B., Jacobsen, S. E. W., Pollard, J. W., Frampton, J., Liu, K. J., Geissmann, F. A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science 336: 86-90, 2012.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Gene Name Synonym
Sp6 transcription factor
Subcellular Location
Nucleus.
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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