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Anti-MIGA1 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Enables protein heterodimerization activity and protein homodimerization activity. Involved in mitochondrial fusion. Located in mitochondrion. Is integral component of plasma membrane.

Synonyms

Protein Bop; BH3-only protein; Retrotransposon Gag-like protein 10; RTL10; BOP, C22orf29

Gene Name

MIGA1

Gene ID

374986

UniProt

Q8NAN2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human MIGA1 recombinant protein (Position: R316-Q562) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed.

Applications

Flow Cytometry

Field of Research

Chemokines, Immunology, Innate Immunity

Purification

Immunogen affinity purified.

Form

Liquid

Function

Could induce apoptosis in a BH3 domain-dependent manner. The interaction network of Bcl-2 family members may play a key role in modulation RTL10/BOP intrinsic apoptotic signaling activity.

References & Citations

1. Gross, M. B. Personal Communication. Baltimore, Md. 1/29/2016. 2. Scott, A. F. Personal Communication. Baltimore, Md. 1/28/2016. 3. Zhang, Y., Liu, X., Bai, J., Tian, X., Zhao, X., Liu, W., Duan, X., Shang, W., Fan, H.-Y., Tong, C. Mitoguardin regulates mitochondrial fusion through MitoPLD and is required for neuronal homeostasis. Molec. Cell 61: 111-124, 2016.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

14377 MW

Applications Notes

6

Gene Name Synonym

Retrotransposon Gag like 10

Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor.

Protein Name

Lymphocyte antigen 6A-2/6E-1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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