Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-MICALL2 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Enables filamin binding activity. Involved in positive regulation of protein targeting to mitochondrion. Predicted to be located in several cellular components, including bicellular tight junction; neuron projection; and recycling endosome. Predicted to colocalize with stress fiber.

Synonyms

Mediator of RNA polymerase II transcription subunit 9; Mediator complex subunit 9; MED9; MED25

Gene Name

MICALL2

Gene ID

79778

UniProt

Q8IY33

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human MICALL2 recombinant protein (Position: K132-Q741) .

Clonality

Polyclonal

Tissue Specificity

Expressed in fetal brain, fetal lung, fetal liver, heart, brain, placenta, lung, liver, muscle, kidney and pancreas.

Applications

Flow Cytometry

Field of Research

Epigenetics and Nuclear Signaling, Mediator Complex, Pol II Transcription, Polymerase Associated Factors, RNA Polymerase, Transcription

Purification

Immunogen affinity purified.

Form

Liquid

Function

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

References & Citations

1. Sakane, A., Yano, T. A., Uchihashi, T., Horikawa, K., Hara, Y., Imoto, I., ... & Sasaki, T. (2021) . JRAB/MICAL-L2 undergoes liquid–liquid phase separation to form tubular recycling endosomes. Communications biology, 4 (1), 551. 2. Zhu, L. Y., Zhang, W. M., Yang, X. M., Cui, L., Li, J., Zhang, Y. L., ... & Zhang, Z. G. (2015) . Silencing of MICAL-L2 suppresses malignancy of ovarian cancer by inducing mesenchymal–epithelial transition. Cancer letters, 363 (1), 71-82. 3. Min, P., Zhao, S., Liu, L., Zhang, Y., Ma, Y., Zhao, X., ... & Du, J. (2019) . MICAL‐L2 potentiates Cdc42‐dependent EGFR stability and promotes gastric cancer cell migration. Journal of cellular and molecular medicine, 23 (6), 4475-4488.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

Mediator complex subunit 9

Subcellular Location

Nucleus .

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

FAM65B, CT (FAM65B, C6orf32, DIFF48, KIAA0386, PL48, Protein FAM65B) (MaxLight 550) discontinued
035472-ML550 100 µL

FAM65B, CT (FAM65B, C6orf32, DIFF48, KIAA0386, PL48, Protein FAM65B) (MaxLight 550) discontinued

Ask
View Details
UQCC (UQCC1) (NM_018244) Human Over-expression Lysate
LC413185 20 µg

UQCC (UQCC1) (NM_018244) Human Over-expression Lysate

Ask
View Details
Mouse SBK2 shRNA Plasmid
abx983862-01 150 µg

Mouse SBK2 shRNA Plasmid

Ask
View Details
Mouse SBK2 shRNA Plasmid
abx983862-02 300 µg

Mouse SBK2 shRNA Plasmid

Ask
View Details
KCNC3 (Potassium Voltage-gated Channel, Shaw-Related Subfamily, Member 3, KSHIIID, KV3.3, SCA13) (APC)
MBS6169602-01 0.1 mL

KCNC3 (Potassium Voltage-gated Channel, Shaw-Related Subfamily, Member 3, KSHIIID, KV3.3, SCA13) (APC)

Ask
View Details
KCNC3 (Potassium Voltage-gated Channel, Shaw-Related Subfamily, Member 3, KSHIIID, KV3.3, SCA13) (APC)
MBS6169602-02 5x 0.1 mL

KCNC3 (Potassium Voltage-gated Channel, Shaw-Related Subfamily, Member 3, KSHIIID, KV3.3, SCA13) (APC)

Ask
View Details