Anti-MIA3 Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
Melanoma inhibitory activity protein 3 (MIA3), also known as transport and Golgi organization protein 1 (TANGO1), is a protein that in humans is encoded by the MIA3 gene on chromosome 1.
Synonyms
S-adenosylmethionine decarboxylase proenzyme; AdoMetDC; SAMDC; 4.1.1.50
Gene Name
MIA3
Gene ID
375056
UniProt
Q5JRA6
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human MIA3 recombinant protein (Position: E54-E1869) .
Clonality
Polyclonal
Tissue Specificity
Widely expressed with higher expression in lung, skeletal muscle, brain, uterus, ovary, thyroid and prostate.
Applications
Flow Cytometry
Field of Research
Cancer, Cell Biology, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction
Purification
Immunogen affinity purified.
Form
Liquid
Function
Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
References & Citations
1. Arndt, S., Bosserhoff, A. K. TANGO is a tumor suppressor of malignant melanoma. Int. J. Cancer 119: 2812-2820, 2006. 2. Bosserhoff, A. K., Moser, M., Buettner, R. Characterization and expression pattern of the novel MIA homolog of TANGO. Gene Expr. Patterns 4: 473-479, 2004. 3. Cauwels, R. G. E. C., De Coster, P. J., Mortier, G. R., Marks, L. A. M., Martens, L. C. Dentinogenesis imperfecta associated with short stature, hearing loss and mental retardation: a new syndrome with autosomal recessive inheritance? J. Oral Path. Med. 34: 444-446, 2005.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Gene Name Synonym
Adenosylmethionine decarboxylase 1
Subcellular Location
Nucleus.
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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