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Anti-MIA3 Antibody Picoband® Fluoro550 Conjugated

Product Specifications

Background

Melanoma inhibitory activity protein 3 (MIA3), also known as transport and Golgi organization protein 1 (TANGO1), is a protein that in humans is encoded by the MIA3 gene on chromosome 1.

Synonyms

S-adenosylmethionine decarboxylase proenzyme; AdoMetDC; SAMDC; 4.1.1.50

Gene Name

MIA3

Gene ID

375056

UniProt

Q5JRA6

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human MIA3 recombinant protein (Position: E54-E1869) .

Clonality

Polyclonal

Tissue Specificity

Widely expressed with higher expression in lung, skeletal muscle, brain, uterus, ovary, thyroid and prostate.

Applications

Flow Cytometry

Field of Research

Cancer, Cell Biology, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.

References & Citations

1. Arndt, S., Bosserhoff, A. K. TANGO is a tumor suppressor of malignant melanoma. Int. J. Cancer 119: 2812-2820, 2006. 2. Bosserhoff, A. K., Moser, M., Buettner, R. Characterization and expression pattern of the novel MIA homolog of TANGO. Gene Expr. Patterns 4: 473-479, 2004. 3. Cauwels, R. G. E. C., De Coster, P. J., Mortier, G. R., Marks, L. A. M., Martens, L. C. Dentinogenesis imperfecta associated with short stature, hearing loss and mental retardation: a new syndrome with autosomal recessive inheritance? J. Oral Path. Med. 34: 444-446, 2005.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

Adenosylmethionine decarboxylase 1

Subcellular Location

Nucleus.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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