Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-MGAT2 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase is an enzyme that in humans is encoded by the MGAT2 gene. The product of this gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in this gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. The coding region of this gene is intronless. Transcript variants with a spliced 5' UTR may exist, but their biological validity has not been determined.

Synonyms

RasGAP-activating-like protein 1; RAS protein activator like 1

Gene Name

MGAT2

Gene ID

4247

UniProt

Q10469

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human MGAT2 recombinant protein (Position: Q81-K427) .

Clonality

Polyclonal

Tissue Specificity

Highly expressed in thyroid and adrenal medulla, lower expression in brain, spinal cord and trachea (PubMed:9751798) . Expressed in melanocytes (PubMed:23999003) .

Applications

Flow Cytometry

Field of Research

Cancer, G Protein Signaling, Oncoproteins/Suppressors, Regulators, Signal Transduction, Signaling Pathway, Small G Proteins, Tumor Suppressors

Purification

Immunogen affinity purified.

Form

Liquid

Function

Probable inhibitory regulator of the Ras-cyclic AMP pathway (PubMed:9751798) . Plays a role in dendrite formation by melanocytes (PubMed:23999003) .

References & Citations

1. Alazami, A. M., Monies, D., Meyer, B. F., Alzahrani, F., Hashem, M., Salih, M. A., Alkuraya, F. S. Congenital disorder of glycosylation IIa: the trouble with diagnosing a dysmorphic inborn error of metabolism. (Letter) Am. J. Med. Genet. 158A: 245-246, 2012. 2. Alkuraya, F. S. Mental retardation, growth retardation, unusual nose, and open mouth: an autosomal recessive entity. Am. J. Med. Genet. 152A: 2160-2163, 2010. 3. Cormier-Daire, V., Amiel, J., Vuillaumier-Barrot, S., Tan, J., Durand, G., Munnich, A., Le Merrer, M., Seta, N. Congenital disorders of glycosylation IIa cause growth retardation, mental retardation, and facial dysmorphism. J. Med. Genet. 37: 875-877, 2000.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

RAS protein activator like 1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Sod3 3'UTR Lenti-reporter-Luc Vector
45105084 1.0 µg

Sod3 3'UTR Lenti-reporter-Luc Vector

Ask
View Details
Phospholipase D2 (PLD2) Bovine ELISA Kit
F8635 96 Tests

Phospholipase D2 (PLD2) Bovine ELISA Kit

Ask
View Details
TCF15, ID (TCF15, BHLHA40, BHLHEC2, Transcription factor 15, Class A basic helix-loop-helix protein 40, Paraxis, Protein bHLH-EC2) (Azide free) (HRP) discontinued
042694-HRP 200 µL

TCF15, ID (TCF15, BHLHA40, BHLHEC2, Transcription factor 15, Class A basic helix-loop-helix protein 40, Paraxis, Protein bHLH-EC2) (Azide free) (HRP) discontinued

Ask
View Details
Recombinant Sorghum bicolor Photosystem II reaction center protein H (psbH)
MBS7027905-01 0.02 mg

Recombinant Sorghum bicolor Photosystem II reaction center protein H (psbH)

Ask
View Details
Recombinant Sorghum bicolor Photosystem II reaction center protein H (psbH)
MBS7027905-02 0.1 mg

Recombinant Sorghum bicolor Photosystem II reaction center protein H (psbH)

Ask
View Details
Recombinant Sorghum bicolor Photosystem II reaction center protein H (psbH)
MBS7027905-03 5x 0.1 mg

Recombinant Sorghum bicolor Photosystem II reaction center protein H (psbH)

Ask
View Details