Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-MAD2L2 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Mitotic spindle assembly checkpoint protein MAD2B is a protein that in humans is encoded by the MAD2L2 gene. The protein encoded by this gene is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The encoded protein, which is similar to MAD2L1, is capable of interacting with ADAM9, ADAM15, REV1, and REV3 proteins.

Synonyms

Calcitonin; Calca; Calc

Gene Name

MAD2L2

Gene ID

10459

UniProt

Q9UI95

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human MAD2L2 recombinant protein (Position: M1-K209) .

Clonality

Polyclonal

Applications

Flow Cytometry

Field of Research

Cardiovascular, Contractility, Neuropeptides, Neuroscience, Neurotransmitter, Vasculature

Purification

Immunogen affinity purified.

Form

Liquid

Function

Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.

References & Citations

1. Bluteau, D., Masliah-Planchon, J., Clairmont, C., Rousseau, A., Ceccaldi, R., Dubois d'Enghien, C., Bluteau, O., Cuccuini, W., Gachet, S., Peffault de Latour, R., Leblanc, T., Socie, G., Baruchel, A., Stoppa-Lyonnet, D., D'Andrea, A. D., Soulier, J. Biallelic inactivation of REV7 is associated with Fanconi anemia. J. Clin. Invest. 126: 3580-3584, 2016. Note: Erratum: J. Clin. Invest. 127: 1117 only, 2017. 2. Boersma, V., Moatti, N., Segura-Bayona, S., Peuscher, M. H., van der Torre, J., Wevers, B. A., Orthwein, A., Durocher, D., Jacobs, J. J. L. MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5-prime end resection. Nature 521: 537-540, 2015. 3. Cahill, D. P., da Costa, L. T., Carson-Walter, E. B., Kinzler, K. W., Vogelstein, B., Lengauer, C. Characterization of MAD2B and other mitotic spindle checkpoint genes. Genomics 58: 181-187, 1999.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

Calcitonin/calcitonin-related polypeptide, alpha

Subcellular Location

Secreted.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Human SLC36A4 Pre-designed siRNA Set A
SI015084A 1 Each

Human SLC36A4 Pre-designed siRNA Set A

Ask
View Details
Rabbit Monoclonal IFITM1 Antibody (021) [Alexa Fluor 647]
NBP2-89230AF647 0.1 mL

Rabbit Monoclonal IFITM1 Antibody (021) [Alexa Fluor 647]

Ask
View Details
Human CTSV (Cathepsin V) ValidElisa Kit
EK340008 96 Well

Human CTSV (Cathepsin V) ValidElisa Kit

Ask
View Details
MIOX Mouse Monoclonal Antibody [Clone ID: LBI5H10]
AMM09953V 100 µL

MIOX Mouse Monoclonal Antibody [Clone ID: LBI5H10]

Ask
View Details
Anti-CAMK2D Antibody (7Z493)
MF-0068729-01 50 µL

Anti-CAMK2D Antibody (7Z493)

Ask
View Details
Anti-CAMK2D Antibody (7Z493)
MF-0068729-02 100 µL

Anti-CAMK2D Antibody (7Z493)

Ask
View Details