Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-MED26 Antibody Picoband®

Boster Bio Anti-MED26 Antibody Picoband® catalog # A09340-1. Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Mediator of RNA polymerase II transcription subunit 26 is an enzyme that in humans is encoded by the MED26 gene. The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor- (TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.

Synonyms

B-cell differentiation antigen CD72; Lyb-2; CD72; CD72

Gene Name

MED26

Gene ID

9441

UniProt

O95402

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human MED26 recombinant protein (Position: N24-D600) .

Clonality

Polyclonal

Tissue Specificity

Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Applications

ELISA, IF, IHC, ICC, WB, Flow Cytometry

Field of Research

Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunology, Lymphoid, Stem Cells

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Plays a role in B-cell proliferation and differentiation.

References & Citations

1. Hartz, P. A. Personal Communication. Baltimore, Md. 1/26/2012. 2. Ryu, S., Zhou, S., Ladurner, A. G., Tjian, R. The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1. Nature 397: 446-450, 1999. 3. Takahashi, H., Parmely, T. J., Sato, S., Tomomori-Sato, C., Banks, C. A. S., Kong, S. E., Szutorisz, H., Swanson, S. K., Martin-Brown, S., Washburn, M. P., Florens, L., Seidel, C. W., Lin, C., Smith, E. R., Shilatifard, A., Conaway, R. C., Conaway, J. W. Human Mediator subunit MED26 functions as a docking site for transcription elongation factors. Cell 146: 92-104, 2011.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

65 kDa

Applications Notes

6

Gene Name Synonym

CD72 molecule

Subcellular Location

Membrane; Single-pass type II membrane protein.

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

CD53 Antibody
V3019SAF-100UG 100 µg

CD53 Antibody

Ask
View Details
TRIM16 Rabbit Polyclonal Antibody
E28PT4735 100 µL

TRIM16 Rabbit Polyclonal Antibody

Ask
View Details
Eotaxin 2 (Biotin) discontinued
E3351-08G-Biotin 100 µL

Eotaxin 2 (Biotin) discontinued

Ask
View Details
RRBP1, CT (RRBP1, KIAA1398, Ribosome-binding protein 1, 180kD ribosome receptor homolog, ES/130-related protein, Ribosome receptor protein) (Azide free) (HRP)
MBS6344077-01 0.2 mL

RRBP1, CT (RRBP1, KIAA1398, Ribosome-binding protein 1, 180kD ribosome receptor homolog, ES/130-related protein, Ribosome receptor protein) (Azide free) (HRP)

Ask
View Details
RRBP1, CT (RRBP1, KIAA1398, Ribosome-binding protein 1, 180kD ribosome receptor homolog, ES/130-related protein, Ribosome receptor protein) (Azide free) (HRP)
MBS6344077-02 5x 0.2 mL

RRBP1, CT (RRBP1, KIAA1398, Ribosome-binding protein 1, 180kD ribosome receptor homolog, ES/130-related protein, Ribosome receptor protein) (Azide free) (HRP)

Ask
View Details
GJB4 Antibody, Biotin conjugated
A67261-100UG 100 µg

GJB4 Antibody, Biotin conjugated

Ask
View Details