Anti-NUP37 Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
Nucleoporin 37 (Nup37) is a protein that in humans is encoded by the NUP37 gene. Nuclear pore complexes (NPCs) are used for transporting macromolecules between the cytoplasm and the nucleus. NPCs consist of multiple copies of 30 distinct proteins (nucleoporins), which assemble into biochemically-separable subcomplexes. The protein encoded by this gene is part of a subcomplex (Nup107-160) that is required for proper NPC function as well as for normal kinetochore-microtubule interaction and mitosis.
Synonyms
Solute carrier family 2, facilitated glucose transporter member 6; Glucose transporter type 6; GLUT-6; Glucose transporter type 9; GLUT-9; SLC2A6; GLUT9
Gene Name
NUP37
Gene ID
79023
UniProt
Q8NFH4
Host
Rabbit
Reactivity
Human, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human NUP37 recombinant protein (Position: R7-D231) .
Clonality
Polyclonal
Tissue Specificity
Highly expressed in brain, spleen and peripheral blood leukocytes.
Applications
Flow Cytometry
Field of Research
Cancer, Channels, Metabolism, Plasma Membrane, Signal Transduction
Purification
Immunogen affinity purified.
Form
Liquid
Function
Facilitative glucose transporter; binds cytochalasin B with low affinity.
References & Citations
1. Braun, D. A., Lovric, S., Schapiro, D., Schneider, R., Marquez, J., Asif, M., Hussain, M. S., Daga, A., Widneier, E., Rao, J., Ashraf, S., Tan, W., and 46 others. Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome. J. Clin. Invest. 128: 4313-4328, 2018. 2. Cronshaw, J. M., Krutchinsky, A. N., Zhang, W., Chait, B. T., Matunis, M. J. Proteomic analysis of the mammalian nuclear pore complex. J. Cell Biol. 158: 915-927, 2002. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 3/16/2005.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Gene Name Synonym
Solute carrier family 2 member 6
Subcellular Location
Cell membrane. Multi-pass membrane protein.
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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