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Anti-PTGR1 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants.

Synonyms

Gap junction gamma-1 protein; Connexin-45; Cx45; Gap junction alpha-7 protein; GJC1; GJA7

Gene Name

PTGR1

Gene ID

22949

UniProt

Q14914

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human PTGR1 recombinant protein (Position: T8-A329) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed.

Applications

Flow Cytometry

Field of Research

Cell Adhesion, Cytoskeleton/ECM, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

References & Citations

1. Boll, W., Schmid-Chanda, T., Semenza, G., Mantei, N. Messenger RNAs expressed in intestine of adult but not baby rabbits: isolation of cognate cDNAs and characterization of a novel brush border protein with esterase and phospholipase activity. J. Biol. Chem. 268: 12901-12911, 1993. 2. Gross, M. B. Personal Communication. Baltimore, Md. 3/26/2014. 3. Yokomizo, T., Izumi, T., Takahashi, T., Kasama, T., Kobayashi, Y., Sato, F., Taketani, Y., Shimizu, T. Enzymatic inactivation of leukotriene B4 by a novel enzyme found in the porcine kidney: purification and properties of leukotriene B4 12-hydroxydehydrogenase. J. Biol. Chem. 268: 18128-18135, 1993.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

45470 MW

Applications Notes

6

Gene Name Synonym

Gap junction gamma-1 protein

Subcellular Location

Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

Protein Name

Gap junction gamma-1 protein

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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