Chlorquinaldol
Chlorquinaldol (Chloquinan) is an antibacterial agent with the potential use in topical skin conditions and vaginal infections. Chlorquinaldol is a β-catenin/TCF4 inhibitor, showing anti-proliferation, anti-migration, and apoptosis-inducing activity in cancer cells[1][2].
Product Specifications
CAS Number
72-80-0
Product Name Alternative
Chloquinan
UNSPSC
12352005
Hazard Statement
H302
Target
Antibiotic; Apoptosis; Bacterial; Fungal; β-catenin
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/Chlorquinaldol.html
Purity
98.69
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC1=C2N=C(C)C=CC2=C(Cl)C=C1Cl
Molecular Formula
C10H7Cl2NO
Molecular Weight
228.08
Precautions
H302
References & Citations
[1]Bortolin M, et al. In vitro Antimicrobial Activity of Chlorquinaldol against Microorganisms Responsible for Skin and Soft Tissue Infections: Comparative Evaluation with Gentamicin and Fusidic Acid. Front Microbiol. 2017 Jun 8;8:1039.|[2]Wang L, et al. Chlorquinaldol targets the β-catenin and T-cell factor 4 complex and exerts anti-colorectal cancer activity. Pharmacol Res. 2020 Sep;159:104955.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Frequently Asked Questions
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