5,7,3'-Tri-O-methyl (-) -epicatechin

5,7,3' -tri-O-Methyl (-) -epicatechin (Compound 13) is a phospholipase Cγ1 (PLCγ1) inhibitor. 5,7,3' -tri-o-methyl (-) -epicatechin has a methylene dioxy benzene ring and can express inhibitory activity against PLCγ1. 5,7,3' -tri-O-Methyl (-) -epicatechin can be used in the study of chemotherapy and chemopexic agents for cancer [1].

Product Specifications

CAS Number

[97914-19-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/5-7-3-tri-o-methyl-minus-epicatechin.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O[C@H]1[C@@H](C2=CC=C(O)C(OC)=C2)OC3=CC(OC)=CC(OC)=C3C1

Molecular Formula

C18H20O6

Molecular Weight

332.35

Precautions

H302, H315, H319, H335

References & Citations

[1]Lee JS, et al. Inhibition of phospholipase Cgamma1 and cancer cell proliferation by lignans and flavans from Machilus thunbergii. Arch Pharm Res. 2004 Oct;27 (10) :1043-7