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Anti-SULT1C4 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Sulfotransferase 1C4 is an enzyme that in humans is encoded by the SULT1C4 gene. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds.

Synonyms

RNA-binding protein Nova-2; Astrocytic NOVA1-like RNA-binding protein; Neuro-oncological ventral antigen 2; NOVA2; ANOVA; NOVA3

Gene Name

SULT1C4

Gene ID

27233

UniProt

O75897

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human SULT1C4 recombinant protein (Position: M1-F302) .

Clonality

Polyclonal

Tissue Specificity

Brain. Expression restricted to astrocytes.

Applications

Flow Cytometry

Field of Research

Channels, Metabolism, Plasma Membrane, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

May regulate RNA splicing or metabolism in a specific subset of developing neurons. Binds single strand RNA.

References & Citations

1. Freimuth, R. R., Raftogianis, R. B., Wood, T. C., Moon, E., Kim, U.-J., Xu, J., Siciliano, M. J., Weinshilboum, R. M. Human sulfotransferases SULT1C1 and SULT1C2: cDNA characterization, gene cloning, and chromosomal localization. Genomics 65: 157-165, 2000. 2. Sakakibara, Y., Yanagisawa, K., Katafuchi, J., Ringer, D. P., Takami, Y., Nakayama, T., Suiko, M., Liu, M.-C. Molecular cloning, expression, and characterization of novel human SULT1C sulfotransferases that catalyze the sulfonation of N-hydroxy-2-acetylaminofluorene. J. Biol. Chem. 273: 33929-33935, 1998.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

29370 MW

Applications Notes

6

Gene Name Synonym

NOVA alternative splicing regulator 2

Subcellular Location

Nucleus.

Protein Name

Aquaporin-6

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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