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Anti-NECAB1 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

NECAB1, also named as EFCBP1, is a brain-specifically expressed gene with highest abundance in temporal lobe, encodes a protein containing EF-hand and antibiotic biosynthesis monooxygenase domains Short Communication.

Synonyms

RNA-binding protein 47; RNA-binding motif protein 47; RBM47

Gene Name

NECAB1

Gene ID

64168

UniProt

Q8N987

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human NECAB1 recombinant protein (Position: E16-E296) .

Clonality

Polyclonal

Tissue Specificity

Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon. .

Applications

Flow Cytometry

Field of Research

Chromatin Binding Proteins, DNA/RNA Binding, Epigenetics and Nuclear Signaling

Purification

Immunogen affinity purified.

Form

Liquid

Function

Can bind to the surface of B-lymphoma cells, but not T- lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.

References & Citations

1. Wu, H. , Li, D. , Shan, Y. , Wan, B. , Hexige, S. , & Guo, J. , et al. (2007) . Efcbp1/necab1, a brain-specifically expressed gene with highest abundance in temporal lobe, encodes a protein containing ef-hand and antibiotic biosynthesis monooxygenase domains. Dna Seq, 18 (1), 73-79. 2. Zhang, M. D. , Barde, S. , Szodorai, E. , Josephson, A. , Mitsios, N. , & Watanabe, M. , et al. (2016) . Comparative anatomical distribution of neuronal calcium-binding protein (necab) 1 and -2 in rodent and human spinal cord. Brain Structure & Function, 221 (7), 1-21. 3. Sugita, S. , Ho, A. , & T.C. Südhof. (2002) . Necabs: a family of neuronal ca (2+) -binding proteins with an unusual domain structure and a restricted expression pattern. Neuroscience, 112 (1), 51-63.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

64099 MW

Applications Notes

6

Gene Name Synonym

RNA-binding protein 47

Subcellular Location

Nucleus .

Protein Name

Follicular dendritic cell secreted peptide

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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