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Anti-NR1/NDOR1 Antibody Picoband® Fluoro647 Conjugated

Selected Variant

A09352-1-Fluoro647

Size: 100 µg/Vial

Product Specifications

Background

NADPH-dependent diflavin oxidoreductase 1 is an enzyme that in humans is encoded by the NDOR1 gene. This gene encodes an NADPH-dependent diflavin reductase that contains both flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) binding domains. The encoded protein catalyzes the transfer of electrons from NADPH through FAD and FMN cofactors to potential redox partners. Alternative splicing results in multiple transcript variants.

Synonyms

B-cell differentiation antigen CD72; Lyb-2; CD72; CD72

Gene Name

NDOR1

Gene ID

27158

UniProt

Q9UHB4

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human NR1/NDOR1 recombinant protein (Position: R31-Q407) .

Clonality

Polyclonal

Tissue Specificity

Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Applications

Flow Cytometry

Field of Research

Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunology, Lymphoid, Stem Cells

Purification

Immunogen affinity purified.

Form

Liquid

Function

Plays a role in B-cell proliferation and differentiation.

References & Citations

1. Kwasnicka, D. A., Krakowiak, A., Thacker, C., Brenner, C., Vincent, S. R. Coordinate expression of NADPH-dependent flavin reductase, Fre-1, and Hint-related 7meGMP-ed hydrolase, DCS-1. J. Biol. Chem. 278: 39051-39058, 2003. 2. Kwasnicka-Crawford, D. A., Vincent, S. R. Role of a novel dual flavin reductase (NR1) and an associated histidine triad protein (DCS-1) in menadione-induced cytotoxicity. Biochem. Biophys. Res. Commun. 336: 565-571, 2005. 3. Paine, M. J. I., Garner, A. P., Powell, D., Sibbald, J., Sales, M., Pratt, N., Smith, T., Tew, D. G., Wolf, C. R. Cloning and characterization of a novel human dual flavin reductase. J. Biol. Chem. 275: 1471-1478, 2000.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

CD72 molecule

Subcellular Location

Membrane; Single-pass type II membrane protein.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Price

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