Anti-TTC39A Antibody Picoband® Fluoro550 Conjugated

Product Specifications

Background

TTC39A (Tetratricopeptide Repeat Domain 39A) is located on human chromosome 5p13.3. The TTC39A protein is ubiquitously expressed in brain, colon and other tissues. The TTC39A (also known as DEME-6; C1orf34) gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. 232 organisms have orthologs with human gene TTC39A. An important paralog of this gene is TTC39B.

Synonyms

Kelch repeat and BTB domain-containing protein 2; BTB and kelch domain-containing protein 1; KBTBD2; BKLHD1; KIAA1489

Gene Name

TTC39A

Gene ID

22996

UniProt

Q5SRH9

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human TTC39A recombinant protein (Position: E18-E489) .

Clonality

Polyclonal

Tissue Specificity

Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Applications

Flow Cytometry

Field of Research

Cell Biology

Purification

Immunogen affinity purified.

Form

Liquid

Function

Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.

References & Citations

1. Gross, M. B. Personal Communication. Baltimore, Md. 5/24/2022. 2. Seki, N., Ohira, M., Nagase, T., Ishikawa, K., Miyajima, N., Nakajima, D., Nomura, N., Ohara, O. Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. DNA Res. 4: 345-349, 1997.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

24145 MW

Applications Notes

Gene Name Synonym

Kelch repeat and BTB domain containing 2

Subcellular Location

Cul3-RING ubiquitin ligase complex.

Protein Name

Transmembrane protein 240

Isotype

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

More Discoveries

Explore Other Products

Browse additional items from our catalog

TP323304L 1 mg

RNF14 (NM_004290) Human Recombinant Protein

View Details

ELI-09036h 96 Tests

Human Uncharacterized protein DNAH10OS, DNAH10OS ELISA KIT

View Details

VG9C60-01 1 mg

Recombinant Leptospira interrogans Lipoprotein LipL21

View Details

VG9C60-02 100 µg

Recombinant Leptospira interrogans Lipoprotein LipL21

View Details

456474-01 10 mg

Mono-O-acetyl Fingolimod

View Details

456474-02 25 mg

Mono-O-acetyl Fingolimod

View Details

Anti-TTC39A Antibody Picoband® Fluoro550 Conjugated

Product Specifications

Background

Synonyms

Gene Name

Gene ID

UniProt

Host

Reactivity

Cross Reactivity

Immunogen

Clonality

Tissue Specificity

Applications

Field of Research

Purification

Form

Function

References & Citations

Storage Conditions

Calculated Molecular Weight

Applications Notes

Gene Name Synonym

Subcellular Location

Protein Name

Isotype

Contents

Explore Other Products

RNF14 (NM_004290) Human Recombinant Protein

Human Uncharacterized protein DNAH10OS, DNAH10OS ELISA KIT

Recombinant Leptospira interrogans Lipoprotein LipL21

Recombinant Leptospira interrogans Lipoprotein LipL21

Mono-O-acetyl Fingolimod

Mono-O-acetyl Fingolimod