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Anti-TTC29 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Involved in cilium movement and cilium organization. Located in sperm flagellum. Implicated in spermatogenic failure 42.

Synonyms

Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; PYROXD1

Gene Name

TTC29

Gene ID

83894

UniProt

Q8NA56

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human TTC29 recombinant protein (Position: D40-R460) .

Clonality

Polyclonal

Tissue Specificity

Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Applications

Flow Cytometry

Field of Research

Cell Biology

Purification

Immunogen affinity purified.

Form

Liquid

Function

Involved in cellular response to oxidative stress.

References & Citations

1. Gross, M. B. Personal Communication. Baltimore, Md. 1/10/2019. 2. Liu, C., He, X., Liu, W., Yang, S., Wang, L., Li, W., Wu, H., Tang, S., Ni, X., Wang, J., Gao, Y., Tian, S., and 12 others. Bi-allelic mutations in TTC29 cause male subfertility with asthenoteratospermia in humans and mice. Am. J. Hum. Genet. 105: 1168-1181, 2019. 3. Lores, P., Dacheux, D., Kherraf, Z.-E., Nsota Mbango, J.-F., Coutton, C., Stouvenel, L., Ialy-Radio, C., Amiri-Yekta, A., Whitfield, M., Schmitt, A., Cazin, C., Givelet, M., and 24 others. Mutations in TTC29, encoding an evolutionarily conserved axonemal protein, result in asthenozoospermia and male infertility. Am. J. Hum. Genet. 105: 1148-1167, 2019.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

24145 MW

Applications Notes

6

Gene Name Synonym

Pyridine nucleotide-disulphide oxidoreductase domain 1

Subcellular Location

Nucleus. Sarcomere.

Protein Name

Transmembrane protein 240

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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