Anti-NEGR1 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
Neuronal growth regulator 1 also known as NEGR1 is a protein which in humans is encoded by the NEGR1 gene. NEGR1 may be involved in cell-adhesion. May function as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain (By similarity) .
Synonyms
Neurocan core protein; Chondroitin sulfate proteoglycan 3; NCAN; CSPG3, NEUR
Gene Name
NEGR1
Gene ID
257194
UniProt
Q7Z3B1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human NEGR1 recombinant protein (Position: Q36-H291) .
Clonality
Polyclonal
Tissue Specificity
Brain.
Applications
Flow Cytometry
Field of Research
Cell Adhesion Proteins, ECM Proteins, Neuroscience
Purification
Immunogen affinity purified.
Form
Liquid
Function
May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM) . Chondroitin sulfate proteoglycan; binds to hyaluronic acid.
References & Citations
1. Funatsu, N., Miyata, S., Kumanogoh, H., Shigeta, M., Hamada, K., Endo, Y., Sokawa, Y., Maekawa, S. Characterization of a novel rat brain glycosylphosphatidylinositol-anchored protein (Kilon), a member of the IgLON cell adhesion molecule family. J. Biol. Chem. 274: 8224-8230, 1999. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 12/11/2009.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
104553 MW
Applications Notes
6
Gene Name Synonym
Neurocan
Subcellular Location
Secreted .
Protein Name
AP-2 complex subunit beta
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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