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Anti-NEGR1 Antibody Picoband®

Boster Bio Anti-NEGR1 Antibody Picoband® catalog # A06730-2. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Neuronal growth regulator 1 also known as NEGR1 is a protein which in humans is encoded by the NEGR1 gene. NEGR1 may be involved in cell-adhesion. May function as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain (By similarity) .

Synonyms

Neurocan core protein; Chondroitin sulfate proteoglycan 3; NCAN; CSPG3, NEUR

Gene Name

NEGR1

Gene ID

257194

UniProt

Q7Z3B1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human NEGR1 recombinant protein (Position: Q36-H291) .

Clonality

Polyclonal

Tissue Specificity

Brain.

Applications

WB, ELISA

Field of Research

Cell Adhesion Proteins, ECM Proteins, Neuroscience

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM) . Chondroitin sulfate proteoglycan; binds to hyaluronic acid.

References & Citations

1. Funatsu, N., Miyata, S., Kumanogoh, H., Shigeta, M., Hamada, K., Endo, Y., Sokawa, Y., Maekawa, S. Characterization of a novel rat brain glycosylphosphatidylinositol-anchored protein (Kilon), a member of the IgLON cell adhesion molecule family. J. Biol. Chem. 274: 8224-8230, 1999. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 12/11/2009.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

104553 MW

Observed Molecular Weight

46 kDa

Gene Name Synonym

Neurocan

Subcellular Location

Secreted .

Protein Name

AP-2 complex subunit beta

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

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