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Anti-NEDD1 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Neural precursor cell expressed, developmentally down-regulated 1, also known as Nedd1, is a human gened and encodes the protein NEDD1. NEDD1 is required for mitosis progression. NEDD1 promotes the nucleation of microtubules from the spindle. This antibody works well in WB, IHC, IP and IF application.

Synonyms

RasGAP-activating-like protein 1; RAS protein activator like 1

Gene Name

NEDD1

Gene ID

121441

UniProt

Q8NHV4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human NEDD1 recombinant protein (Position: D191-E647) .

Clonality

Polyclonal

Tissue Specificity

Highly expressed in thyroid and adrenal medulla, lower expression in brain, spinal cord and trachea (PubMed:9751798) . Expressed in melanocytes (PubMed:23999003) .

Applications

Flow Cytometry

Field of Research

Cancer, G Protein Signaling, Oncoproteins/Suppressors, Regulators, Signal Transduction, Signaling Pathway, Small G Proteins, Tumor Suppressors

Purification

Immunogen affinity purified.

Form

Liquid

Function

Probable inhibitory regulator of the Ras-cyclic AMP pathway (PubMed:9751798) . Plays a role in dendrite formation by melanocytes (PubMed:23999003) .

References & Citations

1. Kumar, S., Tomooka, Y., Noda, M. Identification of a set of genes with developmentally down-regulated expression in the mouse brain. Biochem. Biophys. Res. Commun. 185: 1155-1161, 1992. 2. Takai, S., Yoshida, Y., Noda, M., Yamada, K., Kumar, S. Assignment of the developmentally regulated gene NEDD1 to human chromosome 12q22 by fluorescence in situ hybridization. Hum. Genet. 95: 96-98, 1995.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

RAS protein activator like 1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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