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Anti-NEDD1 Antibody Picoband®

Boster Bio Anti-NEDD1 Antibody Picoband® catalog # A06427-2. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Neural precursor cell expressed, developmentally down-regulated 1, also known as Nedd1, is a human gened and encodes the protein NEDD1. NEDD1 is required for mitosis progression. NEDD1 promotes the nucleation of microtubules from the spindle. This antibody works well in WB, IHC, IP and IF application.

Synonyms

RasGAP-activating-like protein 1; RAS protein activator like 1

Gene Name

NEDD1

Gene ID

121441

UniProt

Q8NHV4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human NEDD1 recombinant protein (Position: D191-E647) .

Clonality

Polyclonal

Tissue Specificity

Highly expressed in thyroid and adrenal medulla, lower expression in brain, spinal cord and trachea (PubMed:9751798) . Expressed in melanocytes (PubMed:23999003) .

Applications

WB, Flow Cytometry, ELISA

Field of Research

Cancer, G Protein Signaling, Oncoproteins/Suppressors, Regulators, Signal Transduction, Signaling Pathway, Small G Proteins, Tumor Suppressors

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Probable inhibitory regulator of the Ras-cyclic AMP pathway (PubMed:9751798) . Plays a role in dendrite formation by melanocytes (PubMed:23999003) .

References & Citations

1. Kumar, S., Tomooka, Y., Noda, M. Identification of a set of genes with developmentally down-regulated expression in the mouse brain. Biochem. Biophys. Res. Commun. 185: 1155-1161, 1992. 2. Takai, S., Yoshida, Y., Noda, M., Yamada, K., Kumar, S. Assignment of the developmentally regulated gene NEDD1 to human chromosome 12q22 by fluorescence in situ hybridization. Hum. Genet. 95: 96-98, 1995.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

70 kDa

Applications Notes

6

Gene Name Synonym

RAS protein activator like 1

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

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