What sizes are available for Anti-PXK Antibody Picoband® Fluoro594 Conjugated?

Anti-PXK Antibody Picoband® Fluoro594 Conjugated is available in the following size(s): 100 µg/Vial.

Is Anti-PXK Antibody Picoband® Fluoro594 Conjugated in stock?

Anti-PXK Antibody Picoband® Fluoro594 Conjugated is currently made to order / not held in immediate stock. Contact us for lead time.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

Anti-PXK Antibody Picoband® Fluoro594 Conjugated

Q: What is the catalog number for Anti-PXK Antibody Picoband® Fluoro594 Conjugated?

The catalog number for Anti-PXK Antibody Picoband® Fluoro594 Conjugated is A07555-1-Fluoro594.

Selected Variant

A07555-1-Fluoro594

Size: 100 µg/Vial

Product Specifications

Background

PX domain containing serine/threonine kinase also known as PXK is a protein which in humans is encoded by the PXK gene. This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE) . Alternative splicing results in multiple transcript variants.

Synonyms

C-C motif chemokine 16; Chemokine CC-4; HCC-4; Chemokine LEC; IL-10-inducible chemokine; LCC-1; Liver-expressed chemokine; Lymphocyte and monocyte chemoattractant; LMC; Monotactin-1; MTN-1; NCC-4; Small-inducible cytokine A16; CCL16; ILINCK; NCC4; SCYA16

Gene Name

PXK

Gene ID

54899

UniProt

Q7Z7A4

Host

Rabbit

Reactivity

Human, Monkey

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human PXK recombinant protein (Position: E5-K576) .

Clonality

Polyclonal

Tissue Specificity

Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma- activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones.

Applications

Flow Cytometry

Field of Research

Angiogenesis, Cardiovascular, Chemokines, Cytokines, Immunology, Innate Immunity, Macrophage/Inflammation

Purification

Immunogen affinity purified.

Form

Liquid

Function

Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.

References & Citations

1. Mao, H., Ferguson, T. S., Cibulsky, S. M., Holmqvist, M., Ding, C., Fei, H., Levitan, I. B. MONaKA, a novel modulator of the plasma membrane Na, K-ATPase. J. Neurosci. 25: 7934-7943, 2005. 2. Zou, X., Qiu, G., Chen, C., Wu, M., Hu, Y., Zheng, H., Li, X., Gu, S., Ji, C., Mao, Y. Expression pattern and subcellular localization of five splice isoforms of human PXK. Int. J. Molec. Med. 16: 701-707, 2005.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

157578 MW

Applications Notes

Gene Name Synonym

C-C motif chemokine ligand 16

Subcellular Location

Secreted.

Protein Name

BAG family molecular chaperone regulator 5

Isotype

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Price

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