Anti-POH1/PSMD14 Antibody Picoband® Fluoro594 Conjugated

Product Specifications

Background

26S proteasome non-ATPase regulatory subunit 14, also known as 26S proteasome non-ATPase subunit Rpn11, is an enzyme that in humans is encoded by the PSMD14 gene. This gene encodes a component of the 26S proteasome. The 26S proteasome is a large multiprotein complex that catalyzes the degradation of ubiquitinated intracellular proteins. The encoded protein is a component of the 19S regulatory cap complex of the 26S proteasome and mediates substrate deubiquitination. A pseudogene of this gene is also located on the long arm of chromosome 2.

Synonyms

Semaphorin-3B; Sema A (V) ; Semaphorin-V; Sema V; SEMA3B; SEMA5; SEMAA

Gene Name

PSMD14

Gene ID

10213

UniProt

O00487

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human POH1/PSMD14 recombinant protein (Position: D21-K310) .

Clonality

Polyclonal

Tissue Specificity

Expressed abundantly but differentially in a variety of neural and nonneural tissues.

Applications

Flow Cytometry

Field of Research

Adapters, Coat Proteins, Cytoplasmic, Protein Trafficking, Signal Transduction, Vesicle Transport

Purification

Immunogen affinity purified.

Form

Liquid

Function

Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.

References & Citations

1. Spataro, V., Toda, T., Craig, R., Seeger, M., Dubiel, W., Harris, A. L., Norbury, C. Resistance to diverse drugs and ultraviolet light conferred by overexpression of a novel human 26 S proteasome subunit. J. Biol. Chem. 272: 30470-30475, 1997. 2. Yao, T., Cohen, R. E. A cryptic protease couples deubiquitination and degradation by the proteasome. Nature 419: 403-407, 2002.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

104553 MW

Applications Notes

Gene Name Synonym

Semaphorin 3B

Subcellular Location

Endoplasmic reticulum. Secreted.

Protein Name

AP-2 complex subunit beta

Isotype

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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Anti-POH1/PSMD14 Antibody Picoband® Fluoro594 Conjugated

Product Specifications

Background

Synonyms

Gene Name

Gene ID

UniProt

Host

Reactivity

Cross Reactivity

Immunogen

Clonality

Tissue Specificity

Applications

Field of Research

Purification

Form

Function

References & Citations

Storage Conditions

Calculated Molecular Weight

Applications Notes

Gene Name Synonym

Subcellular Location

Protein Name

Isotype

Contents

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