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Anti-PSD3 Antibody Picoband® Fluoro594 Conjugated

Product Specifications

Background

PH and SEC7 domain-containing protein 3 is a protein that in humans is encoded by the PSD3 gene. Predicted to enable guanyl-nucleotide exchange factor activity and phospholipid binding activity. Predicted to be involved in regulation of ARF protein signal transduction and regulation of catalytic activity. Predicted to be located in membrane. Predicted to be active in ruffle membrane.

Synonyms

Pre T-cell antigen receptor alpha; pT-alpha; pTa; pT-alpha-TCR; PTCRA

Gene Name

PSD3

Gene ID

23362

UniProt

Q9NYI0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human PSD3 recombinant protein (Position: N15-E475) .

Clonality

Polyclonal

Tissue Specificity

Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.

Applications

Flow Cytometry

Field of Research

Hematopoietic Progenitors, Lymphoid, Stem Cells, T Lymphocytic Lineage

Purification

Immunogen affinity purified.

Form

Liquid

Function

The pre-T-cell receptor complex (composed of PTCRA, TCRB and the CD3 complex) regulates early T-cell development. .

References & Citations

1. Pils, D., Horak, P., Gleiss, A., Sax, C., Fabjani, G., Moebus, V. J., Zielinski, C., Reinthaller, A., Zeillinger, R., Krainer, M. Five genes from chromosomal band 8p22 are significantly down-regulated in ovarian carcinoma: N33 and EFA6R have a potential impact on overall survival. Cancer 104: 2417-2429, 2005.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

41409 MW

Applications Notes

6

Gene Name Synonym

Pre T cell antigen receptor alpha

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

Protein NDRG3

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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