Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-PPM1N Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

Predicted to enable metal ion binding activity and protein serine/threonine phosphatase activity. Predicted to be involved in negative regulation of I-kappaB kinase/NF-kappaB signaling and positive regulation of canonical Wnt signaling pathway. Predicted to be active in cytosol and nucleus.

Synonyms

Kelch repeat and BTB domain-containing protein 2; BTB and kelch domain-containing protein 1; KBTBD2; BKLHD1; KIAA1489

Gene Name

PPM1N

Gene ID

147699

UniProt

Q8N819

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human PPM1N recombinant protein (Position: R36-A430) .

Clonality

Polyclonal

Tissue Specificity

Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Applications

Flow Cytometry

Field of Research

Cell Biology

Purification

Immunogen affinity purified.

Form

Liquid

Function

Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.

References & Citations

1. Zhou, H. , Xu, M. , Huang, Q. , Gates, A. T. , Zhang, X. D. , & Castle, J. C. , et al. (2008) . Genome-scale rnai screen for host factors required for hiv replication. Cell host & microbe, 4 (5), 495-504. 2. Shi, P. , Guo, Y. , Su, Y. , Zhu, M. , & Huang, J. . (2020) . Sumoylation of ddx39a alters binding and export of antiviral transcripts to control innate immunity. The Journal of Immunology, 205 (1), ji2000053. 3. Fasci, D. , Ingen, H. V. , Scheltema, R. A. , & Heck, A. J. R. . (2018) . Histone interaction landscapes visualized by crosslinking mass spectrometry in intact cell nuclei. Molecular & Cellular Proteomics Mcp, 17 (10), mcp.RA118.000924.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

24145 MW

Applications Notes

6

Gene Name Synonym

Kelch repeat and BTB domain containing 2

Subcellular Location

Cul3-RING ubiquitin ligase complex.

Protein Name

Transmembrane protein 240

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

IGSF6, ID (IGSF6, DORA, Immunoglobulin superfamily member 6, Protein DORA) (AP) discontinued
036928-AP 200 µL

IGSF6, ID (IGSF6, DORA, Immunoglobulin superfamily member 6, Protein DORA) (AP) discontinued

Ask
View Details
Bovine Estrogen Receptor (ERβ) ELISA Kit
YP-W78409-01 48 Tests

Bovine Estrogen Receptor (ERβ) ELISA Kit

Ask
View Details
Bovine Estrogen Receptor (ERβ) ELISA Kit
YP-W78409-02 96 Tests

Bovine Estrogen Receptor (ERβ) ELISA Kit

Ask
View Details
Rabbit Polyclonal GPRASP1 Antibody
NBP1-83391 0.1 mL

Rabbit Polyclonal GPRASP1 Antibody

Ask
View Details
Human anti-human IL-33 mAb (A4)
A09D36-A4 1 Each

Human anti-human IL-33 mAb (A4)

Ask
View Details
pGreenFire1-LXRE in LXR alpha (plasmid)
TR102PA-P 10 µg

pGreenFire1-LXRE in LXR alpha (plasmid)

Ask
View Details