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Anti-PGK2 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

This gene is intronless, arose via retrotransposition of the phosphoglycerate kinase 1 gene, and is expressed specifically in the testis. Initially assumed to be a pseudogene, the encoded protein is actually a functional phosphoglycerate kinase that catalyzes the reversible conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate, during the Embden-Meyerhof-Parnas pathway of glycolysis, in the later stages of spermatogenesis.

Synonyms

DnaJ homolog subfamily A member 2; Cell cycle progression restoration gene 3 protein; Dnj3; Dj3; HIRA-interacting protein 4; Renal carcinoma antigen NY-REN-14; DNAJA2; CPR3; HIRIP4

Gene Name

PGK2

Gene ID

5232

UniProt

P07205

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human PGK2 recombinant protein (Position: K267-K350) .

Clonality

Polyclonal

Tissue Specificity

Expressed in fetal and adult brain. Also detected in fetal liver and skeletal muscle, but not in their adult counterparts.

Applications

Flow Cytometry

Field of Research

Organelles, Subcellular Markers, Tags & Cell Markers

Purification

Immunogen affinity purified.

Form

Liquid

Function

Co-chaperone of Hsc70. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B.

References & Citations

1. Chen, S.-H., Donahue, R. P., Scott, C. R. Characterization of phosphoglycerate kinase for human spermatozoa. Fertil. Steril. 27: 699-701, 1976. 2. Eicher, E. M., Cherry, M., Flaherty, L. Autosomal phosphoglycerate kinase linked to mouse major histocompatibility complex. Molec. Gen. Genet. 158: 225-228, 1978. 3. Gartler, S., Riley, D., Eddy, R., Shows, T. A human autosomal phosphoglycerate kinase gene has been assigned to chromosome 19. (Abstract) Cytogenet. Cell Genet. 40: 635-636, 1985.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

DnaJ heat shock protein family (Hsp40) member A2

Subcellular Location

Membrane. Lipid-anchor.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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