Anti-RPS13 Antibody Picoband®

40S ribosomal protein S13 is a protein that in humans is encoded by the RPS13 gene. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S15P family of ribosomal proteins. It is located in the cytoplasm. The protein has been shown to bind to the 5.8S rRNA in rat. The gene product of the E. coli ortholog (ribosomal protein S15) functions at early steps in ribosome assembly. This gene is co-transcribed with two U14 small nucleolar RNA genes, which are located in its third and fifth introns. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

1. Caldwell, G. M., Eddy, R. L., Day, C. D., Haley, L. H., Cooper, P. R., Sait, S. S. J., Hejtmancik, F., Smith, R. J. H., Morton, C. C., Higgins, M. J., Shows, T. B. Mapping of genes and transcribed sequences in a gene rich 400-kb region on human chromosome 11p15.1-p14. Cytogenet. Cell Genet. 92: 103-107, 2001. 2. Chadeneau, C., LeMoullac, B., Denis, M. G. Cloning and analysis of the human S13 ribosomal protein cDNA. Nucleic Acids Res. 21: 2945 only, 1993. 3. Kenmochi, N., Kawaguchi, T., Rozen, S., Davis, E., Goodman, N., Hudson, T. J., Tanaka, T., Page, D. C. A map of 75 human ribosomal protein genes. Genome Res. 8: 509-523, 1998.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.