Anti-PATE1 Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
Predicted to enable acetylcholine receptor regulator activity. Predicted to be involved in regulation of neurotransmitter receptor activity. Predicted to be located in extracellular region.
Synonyms
Transmembrane protein 240; TMEM240; C1orf70
Gene Name
PATE1
Gene ID
160065
UniProt
Q8WXA2
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human PATE1 recombinant protein (Position: S22-L126) .
Clonality
Polyclonal
Tissue Specificity
Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.
Applications
Flow Cytometry
Field of Research
Cell Biology
Purification
Immunogen affinity purified.
Form
Liquid
Function
Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.
References & Citations
1. Bera, T. K., Maitra, R., Iavarone, C., Salvatore, G., Kumar, V., Vincent, J. J., Sathyanarayana, B. K., Duray, P., Lee, B. K., Pastan, I. PATE, a gene expressed in prostate cancer, normal prostate, and testis, identified by a functional genomic approach. Proc. Nat. Acad. Sci. 99: 3058-3063, 2002
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
19908 MW
Applications Notes
6
Gene Name Synonym
Transmembrane protein 240
Subcellular Location
Cell junction, synapse . Cell membrane ; Multi-pass membrane protein .
Protein Name
Transmembrane protein 240
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
032268-PE 200 µL
ATP1A3, ID (ATP1A3, Sodium/potassium-transporting ATPase subunit alpha-3, Na (+) /K (+) ATPase alpha (III) subunit, Sodium pump subunit alpha-3) (PE)
Ask
View Details 
MBS6171366-01 0.1 mL
FOXM1 (Forkhead Box M1, FKHL16, FOXM1B, HFH-11, HFH11, HNF-3, INS-1, MPHOSPH2, MPP-2, MPP2, PIG29, TGT3, TRIDENT) (Biotin)
Ask
View Details MBS6171366-02 5x 0.1 mL
FOXM1 (Forkhead Box M1, FKHL16, FOXM1B, HFH-11, HFH11, HNF-3, INS-1, MPHOSPH2, MPP-2, MPP2, PIG29, TGT3, TRIDENT) (Biotin)
Ask
View Details 
GTR15204086 1 Vial
Lentiviral mouse Snapc4 shRNA (UAS) - Lentiviral mouse Snapc4 shRNA (UAS, iRFP) (25)
Ask
View Details 