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Anti-Rsl1d1 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Ribosomal L1 domain-containing protein 1 is a protein that in humans is encoded by the RSL1D1 gene. Predicted to enable mRNA 3'-UTR binding activity and mRNA 5'-UTR binding activity. Predicted to be involved in maturation of LSU-rRNA; regulation of apoptotic process; and regulation of cellular senescence. Predicted to act upstream of or within regulation of protein localization. Located in nucleolus. Is expressed in several structures, including eye; genitourinary system; liver; lung; and spleen. Orthologous to human RSL1D1 (ribosomal L1 domain containing 1) .

Synonyms

Interleukin-18-binding protein; IL-18BP; Interferon gamma-inducing factor-binding protein; Il18bp; Igifbp

Gene Name

Rsl1d1

Gene ID

66409

UniProt

Q8BVY0

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived mouse Rsl1d1 recombinant protein (Position: E62-N452) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

Flow Cytometry

Field of Research

Interleukins

Purification

Immunogen affinity purified.

Form

Liquid

Function

Binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response (By similarity) . .

References & Citations

1. Ma, L., Chang, N., Guo, S., Li, Q., Zhang, Z., Wang, W., Tong, T. CSIG inhibits PTEN translation in replicative senescence. Molec. Cell. Biol. 28: 6290-6301, 2008. 2. Tong, C., Tan, L., Li, P., Zhu, Y.-S. Identification of a novel nucleus protein involved in the regulation of urokinase in 95D cells. Acta Biochim. Biophys. Sinica 37: 303-309, 2005.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

67166 MW

Applications Notes

6

Gene Name Synonym

Interleukin 18 binding protein

Subcellular Location

Secreted.

Protein Name

Suppressor of tumorigenicity 7 protein

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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