Anti-Cd48 Antibody Picoband® Fluoro594 Conjugated
Product Specifications
Background
CD48 antigen (Cluster of Differentiation 48) also known as B-lymphocyte activation marker (BLAST-1) or signaling lymphocytic activation molecule 2 (SLAMF2) is a protein that in humans is encoded by the CD48 gene. Predicted to enable antigen binding activity and signaling receptor activity. Acts upstream of or within T cell activation and signal transduction. Located in external side of plasma membrane. Is expressed in left lung; liver; right lung; and thymus primordium. Orthologous to human CD48 (CD48 molecule) .
Synonyms
CD48 antigen; B-lymphocyte activation marker BLAST-1; BCM1 surface antigen; Leukocyte antigen MEM-102; SLAM family member 2; SLAMF2; Signaling lymphocytic activation molecule 2; TCT.1; CD48; CD48; BCM1, BLAST1
Gene Name
Cd48
Gene ID
12506
UniProt
P18181
Host
Rabbit
Reactivity
Mouse
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived mouse Cd48 recombinant protein (Position: E77-G219) .
Clonality
Polyclonal
Applications
Flow Cytometry
Field of Research
Cell Type Markers, Immunology
Purification
Immunogen affinity purified.
Form
Liquid
Function
Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.
References & Citations
1. Barton, D. E., Staunton, D., Francke, U. The gene for BLAST1, encoding a B-cell activation marker, is located on chromosome 1, region cen-q32. (Abstract) Cytogenet. Cell Genet. 46: 577 only, 1987. 2. Brown, M. H., Boles, K., van der Merwe, P. A., Kumar, V., Mathew, P. A., Barclay, A. N. 2B4, the natural killer and T cell immunoglobulin superfamily surface protein, is a ligand for CD48. J. Exp. Med. 188: 2083-2093, 1998. 3. Oakey, R. J., Watson, M. L., Seldin, M. F. Construction of a physical map on mouse and human chromosome 1: comparison of 13 Mb of mouse and 11 Mb of human DNA. Hum. Molec. Genet. 1: 613-620, 1992.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
27683 MW
Applications Notes
6
Gene Name Synonym
CD48 antigen
Subcellular Location
Cell membrane ; Lipid-anchor, GPI-anchor .
Protein Name
CD48 antigen
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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