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Anti-Cd48 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

CD48 antigen (Cluster of Differentiation 48) also known as B-lymphocyte activation marker (BLAST-1) or signaling lymphocytic activation molecule 2 (SLAMF2) is a protein that in humans is encoded by the CD48 gene. Predicted to enable antigen binding activity and signaling receptor activity. Acts upstream of or within T cell activation and signal transduction. Located in external side of plasma membrane. Is expressed in left lung; liver; right lung; and thymus primordium. Orthologous to human CD48 (CD48 molecule) .

Synonyms

CD48 antigen; B-lymphocyte activation marker BLAST-1; BCM1 surface antigen; Leukocyte antigen MEM-102; SLAM family member 2; SLAMF2; Signaling lymphocytic activation molecule 2; TCT.1; CD48; CD48; BCM1, BLAST1

Gene Name

Cd48

Gene ID

12506

UniProt

P18181

Host

Rabbit

Reactivity

Mouse

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived mouse Cd48 recombinant protein (Position: E77-G219) .

Clonality

Polyclonal

Applications

Flow Cytometry

Field of Research

Cell Type Markers, Immunology

Purification

Immunogen affinity purified.

Form

Liquid

Function

Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.

References & Citations

1. Barton, D. E., Staunton, D., Francke, U. The gene for BLAST1, encoding a B-cell activation marker, is located on chromosome 1, region cen-q32. (Abstract) Cytogenet. Cell Genet. 46: 577 only, 1987. 2. Brown, M. H., Boles, K., van der Merwe, P. A., Kumar, V., Mathew, P. A., Barclay, A. N. 2B4, the natural killer and T cell immunoglobulin superfamily surface protein, is a ligand for CD48. J. Exp. Med. 188: 2083-2093, 1998. 3. Oakey, R. J., Watson, M. L., Seldin, M. F. Construction of a physical map on mouse and human chromosome 1: comparison of 13 Mb of mouse and 11 Mb of human DNA. Hum. Molec. Genet. 1: 613-620, 1992.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

27683 MW

Applications Notes

6

Gene Name Synonym

CD48 antigen

Subcellular Location

Cell membrane ; Lipid-anchor, GPI-anchor .

Protein Name

CD48 antigen

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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