Anti-TRAPB/SSR2 Antibody Picoband® Fluoro550 Conjugated
Product Specifications
Background
Translocon-associated protein subunit beta also known as TRAP-beta is a protein that in humans is encoded by the SSR2 gene. The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2) . The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23.
Synonyms
Interleukin-17B; IL-17B; Cytokine CX1; Cytokine-like protein ZCYTO7; Neuronal interleukin-17-related factor; Il17b; Nirf, Zcyto7
Gene Name
SSR2
Gene ID
6746
UniProt
P43308
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human TRAPB/SSR2 recombinant protein (Position: E18-E138) .
Clonality
Polyclonal
Tissue Specificity
Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.
Applications
Flow Cytometry
Field of Research
Cytokines, Immunology, Innate Immunity, Interleukins
Purification
Immunogen affinity purified.
Form
Liquid
Function
Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1. .
References & Citations
1. Chinen, K., Sudo, K., Takahashi, E., Nakamura, Y. Isolation and mapping of the human beta-signal sequence receptor gene (SSR2) . Cytogenet. Cell Genet. 70: 215-217, 1995.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Gene Name Synonym
Interleukin 17B
Subcellular Location
Secreted.
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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