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Anti-TRAPB/SSR2 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Translocon-associated protein subunit beta also known as TRAP-beta is a protein that in humans is encoded by the SSR2 gene. The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2) . The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23.

Synonyms

Interleukin-17B; IL-17B; Cytokine CX1; Cytokine-like protein ZCYTO7; Neuronal interleukin-17-related factor; Il17b; Nirf, Zcyto7

Gene Name

SSR2

Gene ID

6746

UniProt

P43308

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human TRAPB/SSR2 recombinant protein (Position: E18-E138) .

Clonality

Polyclonal

Tissue Specificity

Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.

Applications

Flow Cytometry

Field of Research

Cytokines, Immunology, Innate Immunity, Interleukins

Purification

Immunogen affinity purified.

Form

Liquid

Function

Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1. .

References & Citations

1. Chinen, K., Sudo, K., Takahashi, E., Nakamura, Y. Isolation and mapping of the human beta-signal sequence receptor gene (SSR2) . Cytogenet. Cell Genet. 70: 215-217, 1995.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

Interleukin 17B

Subcellular Location

Secreted.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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