Anti-SSBP1 Antibody Picoband® Fluoro550 Conjugated

Product Specifications

Background

Single-stranded DNA-binding protein, mitochondrial is a protein that in humans is encoded by the SSBP1 gene. SSBP1 is a housekeeping gene involved in mitochondrial biogenesis. It is also a subunit of a single-stranded DNA (ssDNA) -binding complex involved in the maintenance of genome stability.

Synonyms

Protein Dok-7; Downstream of tyrosine kinase 7; DOK7; C4orf25

Gene Name

SSBP1

Gene ID

6742

UniProt

Q04837

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human SSBP1 recombinant protein (Position: M1-E148) .

Clonality

Polyclonal

Tissue Specificity

Preferentially expressed in skeletal muscle and heart. Present in thigh muscle, diaphragm and heart but not in the liver or spleen .

Applications

Flow Cytometry

Field of Research

Adapters, Protein Phosphorylation, Receptor Tyrosine Kinases, Signal Transduction, Transmembrane, Tyrosine Kinases

Purification

Immunogen affinity purified.

Form

Liquid

Function

Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK.

References & Citations

1. Bogenhagen, D. F., Rousseau, D., Burke, S. The layered structure of human mitochondrial DNA nucleoids. J. Biol. Chem. 283: 3665-3675, 2008. 2. Del Dotto, V., Ullah, F., Di Meo, I., Magini, P., Gusic, M., Maresca, A., Caporali, L., Palombo, F., Tagliavini, F., Baugh, E. H., Macao, B., Szilagyi, Z., and 35 others. SSBP1 mutations cause mtDNA depletion underlying a complex optic atrophy disorder. J. Clin. Invest. 130: 108-125, 2020. 3. Huang, J., Gong, Z., Ghosal, G., Chen, J. SOSS complexes participate in the maintenance of genomic stability. Molec. Cell 35: 384-393, 2009.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

67074 MW

Applications Notes

Gene Name Synonym

Docking protein 7

Subcellular Location

Cell membrane, Peripheral membrane protein, Synapse.

Protein Name

Long-chain-fatty-acid--CoA ligase 5

Isotype

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

More Discoveries

Explore Other Products

Browse additional items from our catalog

CS632494 5x 5 µm

Frozen Tissue Sections, Ovary: right

View Details

ORF024615 1.0 µg DNA

MIR4779 ORF Vector (Human) (pORF)

View Details

RC216453A1V 250 µL

Human ATG4B (NM_178326) AAV Particle

View Details

MBS7255251-01 48 Well

Rat Homeobox Protein Hox B8 (HOXB8) ELISA Kit

View Details

MBS7255251-02 96 Well

Rat Homeobox Protein Hox B8 (HOXB8) ELISA Kit

View Details

MBS7255251-03 5x 96 Well

Rat Homeobox Protein Hox B8 (HOXB8) ELISA Kit

View Details

Anti-SSBP1 Antibody Picoband® Fluoro550 Conjugated

Product Specifications

Background

Synonyms

Gene Name

Gene ID

UniProt

Host

Reactivity

Cross Reactivity

Immunogen

Clonality

Tissue Specificity

Applications

Field of Research

Purification

Form

Function

References & Citations

Storage Conditions

Calculated Molecular Weight

Applications Notes

Gene Name Synonym

Subcellular Location

Protein Name

Isotype

Contents

Explore Other Products

Frozen Tissue Sections, Ovary: right

MIR4779 ORF Vector (Human) (pORF)

Human ATG4B (NM_178326) AAV Particle

Rat Homeobox Protein Hox B8 (HOXB8) ELISA Kit

Rat Homeobox Protein Hox B8 (HOXB8) ELISA Kit

Rat Homeobox Protein Hox B8 (HOXB8) ELISA Kit