Anti-OLAH Antibody Picoband®

Enables dodecanoyl-[acyl-carrier-protein] hydrolase activity; myristoyl-[acyl-carrier-protein] hydrolase activity; and palmitoyl-[acyl-carrier-protein] hydrolase activity. Involved in medium-chain fatty acid biosynthetic process. Predicted to be located in cytosol.

Matrix metalloproteinase-16; MMP-16; 3.4.24.-; MMP-X2; Membrane-type matrix metalloproteinase 3; MT-MMP 3; MTMMP3; Membrane-type-3 matrix metalloproteinase; MT3-MMP; MT3MMP; MMP16; MMPX2

Angiogenesis, Cancer, Cardiovascular, Cell Biology, ECM Enzymes, Extracellular Matrix, Invasion/Microenvironment, Metalloprotease, Proteolysis/Ubiquitin, Proteolytic Enzymes

Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.

1. Ritchie, M. K. , Johnson, L. C. , Clodfelter, J. E. , Pemble, C. W. , Fulp, B. E. , & Furdui, C. M. , et al. (2015) . Crystal structure and substrate specificity of human thioesterase 2: insights into the molecular basis for the modulation of fatty acid synthase. Journal of Biological Chemistry, 3520-3530. 2. Nobuo, N. , Yasunori, S. , Takahiro, T. , Hiroaki, O. , Daisuke, O. , & Hanjun, Z. , et al. (2006) . Isolation and expression profiling of genes upregulated in bone marrow-derived mononuclear cells of rheumatoid arthritis patients. Dna Research An International Journal for Rapid Publication of Reports on Genes & Genomes, 13 (4), 169. 3. Grupe, A. , Li, Y. , Rowland, C. , Nowotny, P. , Hinrichs, A. L. , & Smemo, S. , et al. (2006) . A scan of chromosome 10 identifies a novel locus showing strong association with late-onset alzheimer disease. The American Journal of Human Genetics, 78 (1), 78-88.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.