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Anti-RNASE6 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Ribonuclease A family member k6 is a protein that in humans is encoded by the RNASE6 gene. The protein encoded by this gene is a member of the ribonuclease A superfamily and functions in the urinary tract. The protein has broad-spectrum antimicrobial activity against pathogenic bacteria.

Synonyms

RNA-binding protein 47; RNA-binding motif protein 47; RBM47

Gene Name

RNASE6

Gene ID

6039

UniProt

Q93091

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human RNASE6 recombinant protein (Position: P25-L150) .

Clonality

Polyclonal

Tissue Specificity

Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon. .

Applications

Flow Cytometry

Field of Research

Chromatin Binding Proteins, DNA/RNA Binding, Epigenetics and Nuclear Signaling

Purification

Immunogen affinity purified.

Form

Liquid

Function

Can bind to the surface of B-lymphoma cells, but not T- lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.

References & Citations

1. Rosenberg, H. F., Dyer, K. D. Molecular cloning and characterization of a novel human ribonuclease (RNase k6) : increasing diversity in the enlarging ribonuclease gene family. Nucleic Acids Res. 24: 3507-3513, 1996.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

64099 MW

Applications Notes

6

Gene Name Synonym

RNA-binding protein 47

Subcellular Location

Nucleus .

Protein Name

Follicular dendritic cell secreted peptide

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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