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Anti-REP15 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

The protein encoded by this intronless gene interacts with GTP-bound Rab15 and is involved in recycling of transferrin receptor from the endocytic recycling compartment to the cell surface.

Synonyms

RNA-binding protein 47; RNA-binding motif protein 47; RBM47

Gene Name

REP15

Gene ID

387849

UniProt

Q6BDI9

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human REP15 recombinant protein (Position: Q3-L236) .

Clonality

Polyclonal

Tissue Specificity

Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon. .

Applications

Flow Cytometry

Field of Research

Chromatin Binding Proteins, DNA/RNA Binding, Epigenetics and Nuclear Signaling

Purification

Immunogen affinity purified.

Form

Liquid

Function

Can bind to the surface of B-lymphoma cells, but not T- lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.

References & Citations

1. Strick, D. J., Elferink, L. A. Rab15 effector protein: a novel protein for receptor recycling from the endocytic recycling compartment. Molec. Biol. Cell 16: 5699-5709, 2005. 2. Stumpf, A. M. Personal Communication. Baltimore, Md. 09/30/2021.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

64099 MW

Applications Notes

6

Gene Name Synonym

RNA-binding protein 47

Subcellular Location

Nucleus .

Protein Name

Follicular dendritic cell secreted peptide

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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