Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-RASSF2 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Ras association domain-containing protein 2 is a protein that in humans is encoded by the RASSF2 gene. This gene encodes a protein that contains a Ras association domain. Similar to its cattle and sheep counterparts, this gene is located near the prion gene. Two alternatively spliced transcripts encoding the same isoform have been reported.

Synonyms

Long-chain-fatty-acid--CoA ligase 4; Long-chain acyl-CoA synthetase 4; LACS 4; ACSL4; ACS4, FACL4, LACS4

Gene Name

RASSF2

Gene ID

9770

UniProt

P50749

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human RASSF2 recombinant protein (Position: M1-I326) .

Clonality

Polyclonal

Tissue Specificity

Expressed in the prostate gland and prostate cancers.

Applications

Flow Cytometry

Field of Research

Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunoglobulins, Immunology, Lymphoid, Receptors, Stem Cells

Purification

Immunogen affinity purified.

Form

Liquid

Function

Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:24269233, PubMed:22633490, PubMed:21242590) . Preferentially activates arachidonate and eicosapentaenoate as substrates (PubMed:21242590) . Preferentially activates 8,9-EET > 14,15-EET > 5,6-EET > 11,12-EET. Modulates glucose-stimulated insulin secretion by regulating the levels of unesterified EETs (By similarity) . Modulates prostaglandin E2 secretion (PubMed:21242590) .

References & Citations

1. Comincini, S., Castiglioni, B. M., Foti, G. M., Del Vecchio, I., Ferretti, L. Isolation and molecular characterization of rasfadin, a novel gene in the vicinity of the bovine prion gene. Mammalian Genome 12: 150-156, 2001. 2. Donninger, H., Hesson, L., Vos, M., Beebe, K., Gordon, L., Sidransky, D., Liu, J. W., Schlegel, T., Payne, S., Hartmann, A., Latif, F., Clark, G. J. The Ras effector RASSF2 controls the PAR-4 tumor suppressor. Molec. Cell. Biol. 30: 2608-2620, 2010. 3. Nagase, T., Seki, N., Ishikawa, K., Tanaka, A., Nomura, N. Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. DNA Res. 3: 17-24, 1996.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

Acyl-CoA synthetase long chain family member 4

Subcellular Location

Secreted.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Goat High mobility group protein B1 (HMGB-1) ELISA Kit
NSL0621Gt 96 Tests

Goat High mobility group protein B1 (HMGB-1) ELISA Kit

Ask
View Details
Matrix Metalloproteinase 9 (Matrix Metallopeptidase 9, MMP-9, MMP9, 92kD Gelatinase, 92kD Type IV Collagenase, CLG4B, Gelatinase B, GELB, MANDP2) (PE) discontinued
M2425-01H-PE 100 µL

Matrix Metalloproteinase 9 (Matrix Metallopeptidase 9, MMP-9, MMP9, 92kD Gelatinase, 92kD Type IV Collagenase, CLG4B, Gelatinase B, GELB, MANDP2) (PE) discontinued

Ask
View Details
ErbB4 Antibody (ready-to-use)
GWB-D602A2 7 mL

ErbB4 Antibody (ready-to-use)

Ask
View Details
Anti-Fas [R-125224]
MBS488361-01 0.2 mg

Anti-Fas [R-125224]

Ask
View Details
Anti-Fas [R-125224]
MBS488361-02 5x 0.2 mg

Anti-Fas [R-125224]

Ask
View Details
PRL5A1 Adenovirus (Rat)
37689056 1.0 mL

PRL5A1 Adenovirus (Rat)

Ask
View Details