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Anti-AP-B/RNPEP Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Aminopeptidase B is an enzyme that in humans is encoded by the RNPEP gene. Predicted to enable metalloaminopeptidase activity. Predicted to be involved in proteolysis. Located in extracellular exosome.

Synonyms

RNA-binding protein Nova-2; Astrocytic NOVA1-like RNA-binding protein; Neuro-oncological ventral antigen 2; NOVA2; ANOVA; NOVA3

Gene Name

RNPEP

Gene ID

6051

UniProt

Q9H4A4

Host

Rabbit

Reactivity

Human, Mouse

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human AP-B/RNPEP recombinant protein (Position: D66-K648) .

Clonality

Polyclonal

Tissue Specificity

Brain. Expression restricted to astrocytes.

Applications

Flow Cytometry

Field of Research

Channels, Metabolism, Plasma Membrane, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

May regulate RNA splicing or metabolism in a specific subset of developing neurons. Binds single strand RNA.

References & Citations

1. Aurich-Costa, J., Cadel, S., Gouzy, C., Foulon, T., Cherif, D., Cohen, P. Assignment of the aminopeptidase B gene (RNPEP) to human chromosome 1 band q32 by in situ hybridization. Cytogenet. Cell Genet. 79: 143-144, 1997. 2. Cadel, S., Foulon, T., Viron, A., Balogh, A., Midol-Monnet, S., Noel, N., Cohen, P. Aminopeptidase B from the rat testis is a bifunctional enzyme structurally related to leukotriene-A4 hydrolase. Proc. Nat. Acad. Sci. 94: 2963-2968, 1997. 3. Cadel, S., Pierotti, A. R., Foulton, T., Creminon, C., Barre, N., Segretain, D., Cohen, P. Aminopeptidase-B in the rat testes: isolation, functional properties and cellular localization in the seminiferous tubules. Molec. Cell. Endocr. 110: 149-160, 1995.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

29370 MW

Applications Notes

6

Gene Name Synonym

NOVA alternative splicing regulator 2

Subcellular Location

Nucleus.

Protein Name

Aquaporin-6

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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