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Anti-RETSAT Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

In enzymology, an all-trans-retinol 13,14-reductase is an enzyme, encoded by the RETSAT gene. Predicted to enable all-trans-retinol 13,14-reductase activity. Predicted to be involved in retinol metabolic process. Located in membrane.

Synonyms

Interleukin-17B; IL-17B; Cytokine CX1; Cytokine-like protein ZCYTO7; Neuronal interleukin-17-related factor; Il17b; Nirf, Zcyto7

Gene Name

RETSAT

Gene ID

54884

UniProt

Q6NUM9

Host

Rabbit

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human RETSAT recombinant protein (Position: E35-K597) .

Clonality

Polyclonal

Tissue Specificity

Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.

Applications

Flow Cytometry

Field of Research

Cytokines, Immunology, Innate Immunity, Interleukins

Purification

Immunogen affinity purified.

Form

Liquid

Function

Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1. .

References & Citations

1. Hartz, P. A. Personal Communication. Baltimore, Md. 7/26/2017. 2. Moise, A. R., Kuksa, V., Imanishi, Y., Palczewski, K. Identification of all-trans-retinol:all-trans-13,14-dihydroretinol saturase. J. Biol. Chem. 279: 50230-50242, 2004. 3. Schupp, M., Lefterova, M. I., Janke, J., Leitner, K., Cristancho, A. G., Mullican, S. E., Qatanani, M., Szwergold, N., Steger, D. J., Curtin, J. C., Kim, R. J., Suh, M.-J., Albert, M. R., Engeli, S., Gudas, L. J., Lazar, M. A. Retinol saturase promotes adipogenesis and is downregulated in obesity. Proc. Nat. Acad. Sci. 106: 1105-1110, 2009. Note: Erratum: Proc. Nat. Acad. Sci. 106: 4571 only, 2009.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

Interleukin 17B

Subcellular Location

Secreted.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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