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Anti-RBM25 Antibody Picoband® Fluoro488 Conjugated

Selected Variant

A07494-1-Fluoro488

Size: 100 µg/Vial

Product Specifications

Background

RNA-binding protein 25 is a protein that in humans is encoded by the RBM25 gene. Enables mRNA binding activity. Involved in regulation of alternative mRNA splicing, via spliceosome and regulation of apoptotic process. Located in nuclear speck.

Synonyms

Inorganic pyrophosphatase; Pyrophosphate phospho-hydrolase; Ppase; PPA1; IOPPP; PP

Gene Name

RBM25

Gene ID

58517

UniProt

P49756

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human RBM25 recombinant protein (Position: D100-E820) .

Clonality

Polyclonal

Tissue Specificity

Expressed ubiquitously.

Applications

Flow Cytometry

Field of Research

Cancer, Cofactors, Vitamins/Minerals, Metabolism, Pathways and Processes, Signal Transduction, Vitamins/Minerals

Purification

Immunogen affinity purified.

Form

Liquid

Function

Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 (By similarity) . May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding. .

References & Citations

1. Fortes, P., Longman, D., McCracken, S., Ip, J. Y., Poot, R., Mattaj, I. W., Caceres, J. F., Blencowe, B. J. Identification and characterization of RED120: a conserved PWI domain protein with links to splicing and 3-prime-end formation. FEBS Lett. 581: 3087-3097, 2007. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 11/20/2008.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

100 kDa

Applications Notes

6

Gene Name Synonym

Pyrophosphatase (inorganic) 1

Subcellular Location

Cytoplasm.

Protein Name

BAG family molecular chaperone regulator 5

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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