Anti-RBM25 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
RNA-binding protein 25 is a protein that in humans is encoded by the RBM25 gene. Enables mRNA binding activity. Involved in regulation of alternative mRNA splicing, via spliceosome and regulation of apoptotic process. Located in nuclear speck.
Synonyms
Inorganic pyrophosphatase; Pyrophosphate phospho-hydrolase; Ppase; PPA1; IOPPP; PP
Gene Name
RBM25
Gene ID
58517
UniProt
P49756
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human RBM25 recombinant protein (Position: D100-E820) .
Clonality
Polyclonal
Tissue Specificity
Expressed ubiquitously.
Applications
Flow Cytometry
Field of Research
Cancer, Cofactors, Vitamins/Minerals, Metabolism, Pathways and Processes, Signal Transduction, Vitamins/Minerals
Purification
Immunogen affinity purified.
Form
Liquid
Function
Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 (By similarity) . May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding. .
References & Citations
1. Fortes, P., Longman, D., McCracken, S., Ip, J. Y., Poot, R., Mattaj, I. W., Caceres, J. F., Blencowe, B. J. Identification and characterization of RED120: a conserved PWI domain protein with links to splicing and 3-prime-end formation. FEBS Lett. 581: 3087-3097, 2007. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 11/20/2008.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
100 kDa
Applications Notes
6
Gene Name Synonym
Pyrophosphatase (inorganic) 1
Subcellular Location
Cytoplasm.
Protein Name
BAG family molecular chaperone regulator 5
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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