Anti-TMEM104 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

Transmembrane protein 104 (TMEM104) is a protein that in humans is encoded by the TMEM104 gene. Predicted to be integral component of membrane.

Synonyms

Kelch repeat and BTB domain-containing protein 2; BTB and kelch domain-containing protein 1; KBTBD2; BKLHD1; KIAA1489

Gene Name

TMEM104

Gene ID

54868

UniProt

Q8NE00

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human TMEM104 recombinant protein (Position: D88-D448) .

Clonality

Polyclonal

Tissue Specificity

Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Applications

Flow Cytometry

Field of Research

Cell Biology

Purification

Immunogen affinity purified.

Form

Liquid

Function

Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.

References & Citations

1. Shi, P. , Guo, Y. , Su, Y. , Zhu, M. , & Huang, J. . (2020) . Sumoylation of ddx39a alters binding and export of antiviral transcripts to control innate immunity. The Journal of Immunology, 205 (1), ji2000053. 2. Huttlin, E. , Ting, L. , Bruckner, R. , Gebreab, F. , Gygi, M. , & Szpyt, J. , et al. (2015) . The bioplex network: a systematic exploration of the human interactome. Cell, 162 (2), 425-440. 3. Ota, T. , Suzuki, Y. , Nishikawa, T. , Otsuki, T. , & Sugano, S. . (2004) . Complete sequencing and characterization of 21,243 full-length human cdnas. Nature Genetics, 36 (1), 40-45.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

24145 MW

Applications Notes

Gene Name Synonym

Kelch repeat and BTB domain containing 2

Subcellular Location

Cul3-RING ubiquitin ligase complex.

Protein Name

Transmembrane protein 240

Isotype

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

More Discoveries

Explore Other Products

Browse additional items from our catalog

GTR15132899 1 Vial

Lentiviral human ATP13A5 shRNA (UAS) - Lentiviral human ATP13A5 shRNA (UAS, RFP) (25)

View Details

abx213659-01 50 µL

Ring Finger Protein 185 (RNF185) Antibody

View Details

abx213659-02 100 µL

Ring Finger Protein 185 (RNF185) Antibody

View Details

bs-6058R-HRP 100 µL

Nicastrin Polyclonal Antibody, HRP Conjugated

View Details

HY-P4515-01 5 mg

Z-Phe-Arg-pNA

View Details

HY-P4515-02 10 mg

Z-Phe-Arg-pNA

View Details

Anti-TMEM104 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

Synonyms

Gene Name

Gene ID

UniProt

Host

Reactivity

Cross Reactivity

Immunogen

Clonality

Tissue Specificity

Applications

Field of Research

Purification

Form

Function

References & Citations

Storage Conditions

Calculated Molecular Weight

Applications Notes

Gene Name Synonym

Subcellular Location

Protein Name

Isotype

Contents

Explore Other Products

Lentiviral human ATP13A5 shRNA (UAS) - Lentiviral human ATP13A5 shRNA (UAS, RFP) (25)

Ring Finger Protein 185 (RNF185) Antibody

Ring Finger Protein 185 (RNF185) Antibody

Nicastrin Polyclonal Antibody, HRP Conjugated

Z-Phe-Arg-pNA

Z-Phe-Arg-pNA