Anti-RAVER1 Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
Ribonucleoprotein, PTB-binding 1 (also known as RAVER1), is a human gene. Enables RNA binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in cytoplasm. Predicted to be active in nucleus.
Synonyms
B-cell differentiation antigen CD72; Lyb-2; CD72; CD72
Gene Name
RAVER1
Gene ID
125950
UniProt
Q8IY67
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human RAVER1 recombinant protein (Position: D209-H567) .
Clonality
Polyclonal
Tissue Specificity
Pre-B-cells and B-cells but not terminally differentiated plasma cells.
Applications
Flow Cytometry
Field of Research
Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunology, Lymphoid, Stem Cells
Purification
Immunogen affinity purified.
Form
Liquid
Function
Plays a role in B-cell proliferation and differentiation.
References & Citations
1. Gromak, N., Rideau, A., Southby, J., Scadden, A. D. J., Gooding, C., Huttelmaier, S., Singer, R. H., Smith, C. W. J. The PTB interacting protein raver1 regulates alpha-tropomyosin alternative splicing. EMBO J. 22: 6356-6364, 2003. 2. Huttelmaier, S., Illenberger, S., Grosheva, I., Rudiger, M., Singer, R. H., Jockusch, B. M. Raver1, a dual compartment protein, is a ligand for PTB/hnRNP1 and microfilament attachment proteins. J. Cell Biol. 155: 775-785, 2001. 3. Nagase, T., Kikuno, R., Ohara, O. Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. DNA Res. 8: 319-327, 2001.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Gene Name Synonym
CD72 molecule
Subcellular Location
Membrane; Single-pass type II membrane protein.
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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